This activity was originally presented at the 2026 HOPA
Annual Conference in New Orleans, LA.
The treatment landscape for B-cell non-Hodgkin lymphomas, particularly diffuse large B-cell lymphoma and follicular lymphoma, has evolved rapidly with the introduction of bispecific antibodies (BsAbs). These immunotherapies are increasingly incorporated into practice, raising key questions around sequencing, comparative efficacy, and real-world implementation. As BsAbs transition from inpatient to outpatient and community oncology settings, they offer opportunities to expand access while introducing clinical and operational complexities, including standardized monitoring and management of cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome. Oncology pharmacists play a critical role across this continuum by interpreting emerging evidence, developing step-up dosing and toxicity management protocols, and operationalizing label-directed safety and monitoring requirements. This multidisciplinary panel will examine practical strategies to support evidence-based decision-making, optimize outpatient workflows, and safely implement BsAbs in patients with DLBCL and follicular lymphoma through case-based discussion.
Target audience: Oncology pharmacists
Type of activity: Application
Release date: April 15, 2026
Expiration date: April 15, 2027
Learner level: Advanced
Time to complete activity: 1.0 hour
Fee: Free
Educational Objectives
At the completion of this activity, participants will be able to:
- Apply emerging clinical evidence of bispecific antibodies in diffuse large B-cell lymphoma and follicular lymphoma to guide pharmacist-driven integration into evolving sequencing pathways
- Prioritize multidisciplinary approaches to adverse effect recognition and escalation in outpatient settings, ensuring pharmacists play a central role in patient education, toxicity grading, and continuity of care
- Employ best practices for pharmacist-led operational integration, including order set builds, compounding/verification, and infusion workflows, to reduce error risk and ensure patient safety
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