Cool Solutions: Non-Hormonal Advances in Vasomotor Symptoms Treatment

Program Description

For many women, vasomotor symptoms (VMS) are more than a transient occurrence, as they may represent a chronic, debilitating burden that can negatively impact sleep, mental health, and professional productivity for a decade or more. Despite this high prevalence, many women still find themselves searching for relief due to contraindications to hormone therapy, safety concerns, or a lack of awareness regarding emerging alternatives. This webinar provides a critical clinical update on the shifting management landscape, anchored in the modern understanding of the KNDy neuron network as the primary driver of menopausal thermoregulatory dysfunction. New therapeutic targets have emerged that move beyond traditional hormone therapy. The program will analyze the limitations of current hormone therapy options and potential place in therapy of off-label non-hormonal options, while providing a deep dive into investigational NK3R and dual NK1/3 receptor antagonists. Participants will review safety and efficacy data pertaining to these emerging therapies and review strategies to lead shared decision-making conversations, dispel common misconceptions about menopausal health, and ensure patients have equitable access to the most appropriate, individualized therapies during this stage of life.

Target audience: Managed care pharmacists
Type of activity: Application
Release date: June 3, 2026
Expiration date: June 3, 2027
Learner level: Foundational, Intermediate
Time to complete activity: 1.0 hour
Fee: Free

Educational Objectives

At the completion of this activity, participants will be able to:

1. Analyze menopause progression, vasomotor symptom (VMS) risk factors, and limitations of hormonal therapies
2. Compare novel non-hormonal therapies for VMS, including efficacy, safety, dosing, and monitoring
3. Illustrate the pharmacist's role in VMS management and incorporation of emerging therapies

Pharmacy Times Continuing Education™ is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity is approved for 1.0 contact hours (0.10 CEU) under the ACPE universal activity number 0290-0000-26-164-H01-P. The activity is available for CE credit through June 3, 2027.

Instructions for Completing the Activity and Receiving CPE Credit

To receive CPE credit, participants must complete the pretest, review the activity in its entirety, complete the posttest, and complete the online activity evaluation. After successful completion of the online activity evaluation, you can submit your credit to CPE Monitor. You may view your credit within 48 hours at www.mycpemonitor.net. All participants must request credit before the activity expiration date. CE credit will not be issued after this date.

Disclosures

The following contributors have no relevant financial relationships with ineligible companies to disclose:

Faculty

Veronica Vernon, PharmD, BCPS, BCACP, MSCP, FAPhA

Pharmacy Times Continuing Education™ Planning Staff—Jim Palatine, RPh, MBA; Dipti Desai, PharmD, MBA, CHCP; Emily Tyler; Susan Pordon; Brianna Winters; and Chloe Taccetta

Any relevant financial relationships listed for these individuals have been mitigated.

At least one anonymous peer reviewer was used as part of content validation and conflict resolution. The peer reviewer has no relevant financial relationships with ineligible companies to disclose.

Educational Disclaimer

CPE activities are offered solely for educational purposes and do not constitute any form of professional advice or referral. Discussions concerning drugs, dosages, and procedures may reflect the clinical experience of the author(s) or they may be derived from the professional literature or other sources and may suggest uses that are investigational in nature and not approved labeling or indications. Participants are encouraged to refer to primary references or full prescribing information resources.

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