Beyond the Nasal Passage: Managing Chronic Rhinosinusitis With Nasal Polyps With Biologics and Pharmacist-Led Approaches

Program Description

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease characterized by presence of benign nasal polyps, which can contribute to significant quality-of-life impairment. Biologic therapies have demonstrated efficacy in treating patients with severe, uncontrolled CRSwNP, although their use is associated with several challenges. The session will explore the underlying pathophysiology of CRSwNP, driven by type 2 inflammation, and review current treatment guidelines alongside recent clinical data for approved biologics. The discussion will focus on the role of specialty pharmacists in overcoming challenges and gaps in care, specifically addressing strategies for individualized biologic selection, facilitating medication access and coordination, providing patient counseling, and ensuring effective initiation and monitoring of these complex therapies. By synthesizing the latest clinical and real-world data, attendees will be equipped with the practical knowledge necessary to overcome systemic barriers and drive individualized, effective biologic selection for patients with CRSwNP.

Target Audience: Specialty Pharmacist

Type of Activity: Application

Release date: November 21, 2025

Expiration date: November 21, 2026

Learner level: Foundational, Intermediate

Time to complete activity: 1.5 hour

Fee: Free

Educational Objectives

At the completion of this activity, participants will be able to:

• Explain how the underlying inflammatory pathophysiology of chronic rhinosinusitis with nasal polyps (CRSwNP) contribute to disease progression
• Identify clinical evidence, real-world data, and current guidelines that inform appropriate selection of biologic therapy for patients with CRSwNP
• Examine practical approaches to navigate access challenges, including prior authorizations and eligibility criteria to improve cost-effective use of biologic therapies in CRSwNP

Pharmacy Times Continuing Education™ is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity is approved for 1.5 contact hours (0.15 CEU) under the ACPE universal activity number 0290-0000-25-376-H01-P. The activity is available for CE credit through November 21, 2026.

Instructions for Completing the Activity and Receiving CPE Credit

To receive CPE credit, participants must complete the pretest, view the activity in its entirety, complete the posttest, and complete the online activity evaluation. After successful completion of the online activity evaluation, you can submit your credit to CPE Monitor. You may view your credit within 48 hours at www.mycpemonitor.net. All participants must request credit before the activity expiration date. CE credit will not be issued after this date.

Disclosures

The following contributors have no relevant financial relationships with ineligible companies to disclose:

Faculty

Shannon M. Rotolo, PharmD, BCPS

Pharmacy Times Continuing Education™ Planning Staff—Jim Palatine, RPh, MBA; Dipti Desai, PharmD, MBA, CHCP; Victoria Chirdo; Susan Pordon; Brianna Winters; and Chloe Taccetta have no relevant financial relationships with ineligible companies to disclose.

Pharmacy Times® Editorial Staff— Aislinn Antrim

Any relevant financial relationships listed for these individuals have been mitigated.

At least one anonymous peer reviewer was used as part of content validation and conflict resolution. The peer reviewer has no relevant financial relationships with ineligible companies to disclose.

Educational Disclaimer

CPE activities are offered solely for educational purposes and do not constitute any form of professional advice or referral. Discussions concerning drugs, dosages, and procedures may reflect the clinical experience of the author(s) or they may be derived from the professional literature or other sources and may suggest uses that are investigational in nature and not approved labeling or indications. Participants are encouraged to refer to primary references or full prescribing information resources.

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